Description |
Hedgehog pathway inhibitor(Cyclopamine) is naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. Cyclopamine is currently being investigated as a treatment agent in basal cell carcinoma, medulloblastoma, and rhabdomyosarcoma, tumors that result from excessive Hh activity, glioblastoma, and as a treatment agent for multiple myeloma. It is currently under phase I of clinical trial.
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